Dispersion from C(α) or N(H): 4D experiments for backbone resonance assignment of intrinsically disordered proteins

Resonance assignment of intrinsically disordered proteins is remarkably challenging due to scant chemical shift dispersion arising from conformational heterogeneity. The challenge is even greater if repeating segments are present in the amino acid sequence. To forward unambiguous resonance assignmen...

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Detalles Bibliográficos
Autores principales: Tossavainen, Helena, Salovaara, Santeri, Hellman, Maarit, Ihalin, Riikka, Permi, Perttu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080685/
https://www.ncbi.nlm.nih.gov/pubmed/31932991
http://dx.doi.org/10.1007/s10858-020-00299-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080685/
https://www.ncbi.nlm.nih.gov/pubmed/31932991
http://dx.doi.org/10.1007/s10858-020-00299-w

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