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Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra
Signal overlapping is a major bottleneck for protein NMR analysis. We propose a new method, stable-isotope-assisted parameter extraction (SiPex), to resolve overlapping signals by a combination of amino-acid selective isotope labeling (AASIL) and tensor decomposition. The basic idea of Sipex is that...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080692/ https://www.ncbi.nlm.nih.gov/pubmed/32002710 http://dx.doi.org/10.1007/s10858-019-00295-9 |