Exome sequencing identifies novel mutation signatures of UV radiation and trichostatin A in primary human keratinocytes

Canonical ultraviolet (UV) mutation type and spectra are traditionally defined by direct sequencing-based approaches to map mutations in a limited number of representative DNA elements. To obtain an unbiased view of genome wide UV mutation features, we performed whole exome-sequencing (WES) to profi...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Yao, Ha, Wootae, Zeng, Wangyong, Queen, Dawn, Liu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080724/
https://www.ncbi.nlm.nih.gov/pubmed/32188867
http://dx.doi.org/10.1038/s41598-020-61807-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080724/
https://www.ncbi.nlm.nih.gov/pubmed/32188867
http://dx.doi.org/10.1038/s41598-020-61807-4

Ejemplares similares