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Exome sequencing identifies novel mutation signatures of UV radiation and trichostatin A in primary human keratinocytes
Canonical ultraviolet (UV) mutation type and spectra are traditionally defined by direct sequencing-based approaches to map mutations in a limited number of representative DNA elements. To obtain an unbiased view of genome wide UV mutation features, we performed whole exome-sequencing (WES) to profi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080724/ https://www.ncbi.nlm.nih.gov/pubmed/32188867 http://dx.doi.org/10.1038/s41598-020-61807-4 |