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Ribitol enhances matriglycan of α-dystroglycan in breast cancer cells without affecting cell growth

The laminin-binding glycan (matriglycan) on α-dystroglycan (α-DG) enables diverse roles, from neuronal development to muscle integrity. Reduction or loss of matriglycan has also been implicated in cancer development and metastasis, and specifically associated with high-grade tumors and poor prognose...

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Detalles Bibliográficos
Autores principales: Lu, Pei J., Tucker, Jason D., Branch, Elizabeth K., Guo, Fei, Blaeser, Anthony R., Lu, Qi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080755/
https://www.ncbi.nlm.nih.gov/pubmed/32188898
http://dx.doi.org/10.1038/s41598-020-61747-z