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Novel strategies for expansion of tooth epithelial stem cells and ameloblast generation

Enamel is secreted by ameloblasts derived from tooth epithelial stem cells (SCs). Humans cannot repair or regenerate enamel, due to early loss of tooth epithelial SCs. Contrarily in the mouse incisors, epithelial SCs are maintained throughout life and endlessly generate ameloblasts, and thus enamel....

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Detalles Bibliográficos
Autores principales: Binder, Martin, Biggs, Leah C., Kronenberg, Mark S., Schneider, Pascal, Thesleff, Irma, Balic, Anamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080756/
https://www.ncbi.nlm.nih.gov/pubmed/32188889
http://dx.doi.org/10.1038/s41598-020-60708-w