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GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes

An important assessment prior to genome assembly and related analyses is genome profiling, where the k-mer frequencies within raw sequencing reads are analyzed to estimate major genome characteristics such as size, heterozygosity, and repetitiveness. Here we introduce GenomeScope 2.0 (https://github...

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Detalles Bibliográficos
Autores principales: Ranallo-Benavidez, T. Rhyker, Jaron, Kamil S., Schatz, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080791/
https://www.ncbi.nlm.nih.gov/pubmed/32188846
http://dx.doi.org/10.1038/s41467-020-14998-3