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Discovery of a bacterial peptide as a modulator of GLP-1 and metabolic disease

Early work in rodents highlighted the gut microbiota’s importance in metabolic disease, including Type II Diabetes Mellitus (T2DM) and obesity. Glucagon-like peptide-1 (GLP-1), an incretin secreted by L-cells lining the gastrointestinal epithelium, has important functions: promoting insulin secretio...

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Detalles Bibliográficos
Autores principales: Tomaro-Duchesneau, Catherine, LeValley, Stephanie L., Roeth, Daniel, Sun, Liang, Horrigan, Frank T., Kalkum, Markus, Hyser, Joseph M., Britton, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080827/
https://www.ncbi.nlm.nih.gov/pubmed/32188864
http://dx.doi.org/10.1038/s41598-020-61112-0