Cargando…
Discovery of a bacterial peptide as a modulator of GLP-1 and metabolic disease
Early work in rodents highlighted the gut microbiota’s importance in metabolic disease, including Type II Diabetes Mellitus (T2DM) and obesity. Glucagon-like peptide-1 (GLP-1), an incretin secreted by L-cells lining the gastrointestinal epithelium, has important functions: promoting insulin secretio...
Autores principales: | Tomaro-Duchesneau, Catherine, LeValley, Stephanie L., Roeth, Daniel, Sun, Liang, Horrigan, Frank T., Kalkum, Markus, Hyser, Joseph M., Britton, Robert A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080827/ https://www.ncbi.nlm.nih.gov/pubmed/32188864 http://dx.doi.org/10.1038/s41598-020-61112-0 |
Ejemplares similares
-
Degradation of the Incretin Hormone Glucagon-Like Peptide-1 (GLP-1) by Enterococcus faecalis Metalloprotease GelE
por: LeValley, Stephanie L., et al.
Publicado: (2020) -
The Gut Microbiota and Human Health with an Emphasis on the Use of Microencapsulated Bacterial Cells
por: Prakash, Satya, et al.
Publicado: (2011) -
Human Intestinal Enteroids With Inducible Neurogenin-3 Expression as a Novel Model of Gut Hormone Secretion
por: Chang-Graham, Alexandra L., et al.
Publicado: (2019) -
Systemic siRNA Delivery via Peptide-Tagged Polymeric Nanoparticles, Targeting PLK1 Gene in a Mouse Xenograft Model of Colorectal Cancer
por: Malhotra, Meenakshi, et al.
Publicado: (2013) -
Microencapsulation for the Therapeutic Delivery of Drugs, Live Mammalian and Bacterial Cells, and Other Biopharmaceutics: Current Status and Future Directions
por: Tomaro-Duchesneau, Catherine, et al.
Publicado: (2013)