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TRIM58 Interacts with Pyruvate Kinase M2 to Inhibit Tumorigenicity in Human Osteosarcoma Cells

BACKGROUND: Tripartite motif containing 58 (TRIM58), an E3 ubiquitin ligase, is reported as a suppressor gene in certain human tumors. However, the biological function of TRIM58 in osteosarcoma (OS) is still less identified. METHODS: In the present study, TRIM58 induced silencing and overexpression...

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Detalles Bibliográficos
Autores principales: Yuan, Peng, Zhou, Yiyi, Wang, Rui, Chen, Shayang, Wang, Qiqi, Xu, Zhujie, Liu, Yi, Yang, Huilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081029/
https://www.ncbi.nlm.nih.gov/pubmed/32219144
http://dx.doi.org/10.1155/2020/8450606