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Pharmacologic Induction of Endotoxin Tolerance in Dendritic Cells by L-Kynurenine

Endotoxin tolerance aims at opposing hyperinflammatory responses to lipopolysaccharide (LPS) exposure. The aryl hydrocarbon receptor (AhR) participates in protection against LPS-mediated tissue damage, as it plays a necessary role in restraining the proinflammatory action of IL-1β and TNF-α while fo...

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Detalles Bibliográficos
Autores principales: Manni, Giorgia, Mondanelli, Giada, Scalisi, Giulia, Pallotta, Maria Teresa, Nardi, Dario, Padiglioni, Eleonora, Romani, Rita, Talesa, Vincenzo Nicola, Puccetti, Paolo, Fallarino, Francesca, Gargaro, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081078/
https://www.ncbi.nlm.nih.gov/pubmed/32226425
http://dx.doi.org/10.3389/fimmu.2020.00292