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Pharmacologic Induction of Endotoxin Tolerance in Dendritic Cells by L-Kynurenine
Endotoxin tolerance aims at opposing hyperinflammatory responses to lipopolysaccharide (LPS) exposure. The aryl hydrocarbon receptor (AhR) participates in protection against LPS-mediated tissue damage, as it plays a necessary role in restraining the proinflammatory action of IL-1β and TNF-α while fo...
Autores principales: | Manni, Giorgia, Mondanelli, Giada, Scalisi, Giulia, Pallotta, Maria Teresa, Nardi, Dario, Padiglioni, Eleonora, Romani, Rita, Talesa, Vincenzo Nicola, Puccetti, Paolo, Fallarino, Francesca, Gargaro, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081078/ https://www.ncbi.nlm.nih.gov/pubmed/32226425 http://dx.doi.org/10.3389/fimmu.2020.00292 |
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