Cargando…
Decay in Retinoic Acid Signaling in Varied Models of Alzheimer’s Disease and In-Vitro Test of Novel Retinoic Acid Receptor Ligands (RAR-Ms) to Regulate Protective Genes
Retinoic acid has been previously proposed in the treatment of Alzheimer’s disease (AD). Here, five transgenic mouse models expressing AD and frontotemporal dementia risk genes (i.e., PLB2(APP), PLB2(TAU), PLB1(Double), PLB1(Triple), and PLB4) were used to investigate if consistent alterations exist...
Autores principales: | Khatib, Thabat, Chisholm, David R., Whiting, Andrew, Platt, Bettina, McCaffery, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081102/ https://www.ncbi.nlm.nih.gov/pubmed/31884477 http://dx.doi.org/10.3233/JAD-190931 |
Ejemplares similares
-
A Bioluminescence Reporter Assay for Retinoic Acid Control of Translation of the GluR1 Subunit of the AMPA Glutamate Receptor
por: Khatib, Thabat, et al.
Publicado: (2019) -
Developmental expression of retinoic acid receptors (RARs)
por: Dollé, Pascal
Publicado: (2009) -
Control of Innate and Adaptive Lymphocytes by the RAR-Retinoic Acid Axis
por: Kim, Chang H.
Publicado: (2018) -
Activation of the CRABPII/RAR pathway by curcumin induces retinoic acid mediated apoptosis in retinoic acid resistant breast cancer cells
por: Thulasiraman, Padmamalini, et al.
Publicado: (2017) -
An Orthologue of the Retinoic Acid Receptor (RAR) Is Present in the Ecdysozoa Phylum Priapulida
por: Fonseca, Elza S. S., et al.
Publicado: (2019)