Probing Protein Denaturation during Size-Exclusion Chromatography Using Native Mass Spectrometry

[Image: see text] Size-exclusion chromatography employing aqueous mobile phases with volatile salts at neutral pH combined with electrospray-ionization mass spectrometry (SEC-ESI-MS) is a useful tool to study proteins in their native state. However, whether the applied eluent conditions actually pre...

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Detalles Bibliográficos
Autores principales: Ventouri, Iro K., Malheiro, Daniel B. A., Voeten, Robert L. C., Kok, Sander, Honing, Maarten, Somsen, Govert W., Haselberg, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081181/
https://www.ncbi.nlm.nih.gov/pubmed/32107919
http://dx.doi.org/10.1021/acs.analchem.9b04961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081181/
https://www.ncbi.nlm.nih.gov/pubmed/32107919
http://dx.doi.org/10.1021/acs.analchem.9b04961

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