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Bringing biocatalytic deuteration into the toolbox of asymmetric isotopic labelling techniques

Enzymes dependent on nicotinamide cofactors are important components of the expanding range of asymmetric synthetic techniques. New challenges in asymmetric catalysis are arising in the field of deuterium labelling, where compounds bearing deuterium ((2)H) atoms at chiral centres are becoming increa...

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Detalles Bibliográficos
Autores principales: Rowbotham, J. S., Ramirez, M. A., Lenz, O., Reeve, H. A., Vincent, K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081218/
https://www.ncbi.nlm.nih.gov/pubmed/32193396
http://dx.doi.org/10.1038/s41467-020-15310-z