A semisynthetic borrelidin analogue BN-3b exerts potent antifungal activity against Candida albicans through ROS-mediated oxidative damage

In the process of investigating the antifungal structure-activity relationships (SAR) of borrelidin and discovering antifungal leads, a semisynthetic borrelidin analogue, BN-3b with antifungal activity against Candida albicans, was achieved. In this study, we found that oxidative damage induced by e...

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Detalles Bibliográficos
Autores principales: Su, Hao, Hu, Caijuan, Cao, Bixuan, Qu, Xiaodan, Guan, Peipei, Mu, Yu, Han, Li, Huang, Xueshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081223/
https://www.ncbi.nlm.nih.gov/pubmed/32193473
http://dx.doi.org/10.1038/s41598-020-61681-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081223/
https://www.ncbi.nlm.nih.gov/pubmed/32193473
http://dx.doi.org/10.1038/s41598-020-61681-0

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