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A semisynthetic borrelidin analogue BN-3b exerts potent antifungal activity against Candida albicans through ROS-mediated oxidative damage
In the process of investigating the antifungal structure-activity relationships (SAR) of borrelidin and discovering antifungal leads, a semisynthetic borrelidin analogue, BN-3b with antifungal activity against Candida albicans, was achieved. In this study, we found that oxidative damage induced by e...
Autores principales: | Su, Hao, Hu, Caijuan, Cao, Bixuan, Qu, Xiaodan, Guan, Peipei, Mu, Yu, Han, Li, Huang, Xueshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081223/ https://www.ncbi.nlm.nih.gov/pubmed/32193473 http://dx.doi.org/10.1038/s41598-020-61681-0 |
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