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Novel B cell-dependent multiple sclerosis model using extracellular domains of myelin proteolipid protein

Therapeutic success of B cell-targeting approaches in multiple sclerosis (MS) has intensified research into the pathogenic and regulatory roles these cells play in demyelinating disease. Dissecting the function of B cells in the MS mouse model experimental autoimmune encephalomyelitis (EAE) is large...

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Detalles Bibliográficos
Autores principales: Boyden, Alexander W., Brate, Ashley A., Karandikar, Nitin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081236/
https://www.ncbi.nlm.nih.gov/pubmed/32193439
http://dx.doi.org/10.1038/s41598-020-61928-w