Cargando…

Selective Intracellular Delivery of Thiolated Cargo to Tumor and Neovasculature Cells Using Histidine-Rich Peptides as Vectors

[Image: see text] Short histidine-rich peptides could serve as novel activatable vectors for delivering cytotoxic payloads to tumor and neovasculature cells. This explorative study reports preliminary results showing that zinc ions, which are found in elevated levels at neovasculature sites, can tri...

Descripción completa

Detalles Bibliográficos
Autores principales: Eksteen, J. Johannes, Ausbacher, Dominik, Vasskog, Terje, Rekdal, Øystein, Svendsen, John S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081261/
https://www.ncbi.nlm.nih.gov/pubmed/32201779
http://dx.doi.org/10.1021/acsomega.9b00700