Whole genome analysis identifies the association of TP53 genomic deletions with lower survival in Stage III colorectal cancer

DNA copy number aberrations (CNA) are frequently observed in colorectal cancers (CRC). There is an urgent need for CNA-based biomarkers in clinics,. n For Stage III CRC, if combined with imaging or pathologic evidence, these markers promise more precise care. We conducted this Stage III specific bio...

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Detalles Bibliográficos
Autores principales: Xia, Li C., Van Hummelen, Paul, Kubit, Matthew, Lee, HoJoon, Bell, John M., Grimes, Susan M., Wood-Bouwens, Christina, Greer, Stephanie U., Barker, Tyler, Haslem, Derrick S., Ford, James M., Fulde, Gail, Ji, Hanlee P., Nadauld, Lincoln D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081316/
https://www.ncbi.nlm.nih.gov/pubmed/32193467
http://dx.doi.org/10.1038/s41598-020-61643-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081316/
https://www.ncbi.nlm.nih.gov/pubmed/32193467
http://dx.doi.org/10.1038/s41598-020-61643-6

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