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Migratory dendritic cells in skin-draining lymph nodes have nickel-binding capabilities

Nickel (Ni) is the most frequent metal allergen and induces Th1-dependent type-IV allergies. In local skin, epidermal Langerhans cells (LCs) and/or dermal dendritic cells (DCs) uptake antigens and migrate to draining lymph nodes (LNs). However, the subsets of antigen-presenting cells that contribute...

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Detalles Bibliográficos
Autores principales: Kuroishi, Toshinobu, Bando, Kanan, Bakti, Reiska Kumala, Ouchi, Gaku, Tanaka, Yukinori, Sugawara, Shunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081353/
https://www.ncbi.nlm.nih.gov/pubmed/32193426
http://dx.doi.org/10.1038/s41598-020-61875-6