Longitudinal phenotype development in a minipig model of neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is a rare, autosomal dominant disease with variable clinical presentations. Large animal models are useful to help dissect molecular mechanisms, determine relevant biomarkers, and develop effective therapeutics. Here, we studied a NF1 minipig model (NF1(+/ex42del)) for...

Descripción completa

Detalles Bibliográficos
Autores principales: Uthoff, Johanna, Larson, Jared, Sato, Takashi S., Hammond, Emily, Schroeder, Kimberly E., Rohret, Frank, Rogers, Christopher S., Quelle, Dawn E., Darbro, Benjamin W., Khanna, Rajesh, Weimer, Jill M., Meyerholz, David K., Sieren, Jessica C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081358/
https://www.ncbi.nlm.nih.gov/pubmed/32193437
http://dx.doi.org/10.1038/s41598-020-61251-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081358/
https://www.ncbi.nlm.nih.gov/pubmed/32193437
http://dx.doi.org/10.1038/s41598-020-61251-4

Ejemplares similares