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Recombinant expression, characterization, and quantification in human cancer cell lines of the Anaplastic Large-Cell Lymphoma-characteristic NPM-ALK fusion protein

Systemic anaplastic large cell lymphoma (ALCL) is an aggressive T-cell lymphoma most commonly seen in children and young adults. The majority of pediatric ALCLs are associated with the t(2;5)(p23;q35) translocation which fuses the Anaplastic Lymphoma Kinase (ALK) gene with the Nucleophosmin (NPM) ge...

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Detalles Bibliográficos
Autores principales: Kourentzi, Katerina, Crum, Mary, Patil, Ujwal, Prebisch, Ana, Chavan, Dimple, Vu, Binh, Zeng, Zihua, Litvinov, Dmitri, Zu, Youli, Willson, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081362/
https://www.ncbi.nlm.nih.gov/pubmed/32193476
http://dx.doi.org/10.1038/s41598-020-61936-w