Efficient and Straightforward Syntheses of Two United States Pharmacopeia Sitagliptin Impurities: 3-Desamino-2,3-dehydrositagliptin and 3-Desamino-3,4-dehydrositagliptin

[Image: see text] Various organic impurities (starting materials, reagents, intermediates, degradation products, by-products, and side products) could be present in active pharmaceutical ingredients affecting their qualities, safeties, and efficacies. Herein, we present the efficient syntheses of tw...

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Detalles Bibliográficos
Autores principales: Sova, Matej, Frlan, Rok, Gobec, Stanislav, Časar, Zdenko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081400/
https://www.ncbi.nlm.nih.gov/pubmed/32201825
http://dx.doi.org/10.1021/acsomega.9b04393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081400/
https://www.ncbi.nlm.nih.gov/pubmed/32201825
http://dx.doi.org/10.1021/acsomega.9b04393

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