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Applying Quality by Design Principles in the Development and Preparation of a New Radiopharmaceutical: Technetium-99m-Imatinib Mesylate

[Image: see text] The clinical impact and accessibility of (99m)Tc tracers for cancer diagnosis would be greatly enhanced by the availability of a new, simple, and easy labeling process and radiopharmaceuticals. In this study, Technetium-99m-imatinib mesylate ([(99m)Tc]TcIMT) was developed and prepa...

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Detalles Bibliográficos
Autores principales: Gundogdu, Evren, Demir, Emine Selin, Özgenç, Emre, Yeğen, Gizem, Aksu, Buket
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081423/
https://www.ncbi.nlm.nih.gov/pubmed/32201818
http://dx.doi.org/10.1021/acsomega.9b04327