Expeditious Green Synthesis of Novel 4-Methyl-1,2,5,6-tetraazafluoranthen-3(2H)-one Analogue from Ninhydrin: N/S-Alkylation and Aza-Michael Addition

[Image: see text] A straightforward green synthesis of 4-methyl-1,2,5,6-tetraazafluoranthen-3(2H)-one 6 is reported from ninhydrin 1 via condensation with ethyl acetoacetate, followed by cyclization with hydrazine hydrate in water as a benign solvent. Tetraazafluoranthen-3-thione 7 was obtained usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Boraei, Ahmed T. A., Ghabbour, Hazem A., Sarhan, Ahmed A. M., Barakat, Assem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081446/
https://www.ncbi.nlm.nih.gov/pubmed/32201835
http://dx.doi.org/10.1021/acsomega.0c00045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081446/
https://www.ncbi.nlm.nih.gov/pubmed/32201835
http://dx.doi.org/10.1021/acsomega.0c00045

Ejemplares similares