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Aged mice show an increased mortality after anesthesia with a standard dose of ketamine/xylazine

Geriatric animal models are crucial for a better understanding and an improved therapy of age-related diseases. We observed a high mortality of aged mice after anesthesia with a standard dose of ketamine/xylazine, an anesthetic regimen frequently used in laboratory veterinary medicine. C57BL/6-N mic...

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Detalles Bibliográficos
Autores principales: Schuetze, Sandra, Manig, Anja, Ribes, Sandra, Nau, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081538/
https://www.ncbi.nlm.nih.gov/pubmed/32257896
http://dx.doi.org/10.1186/s42826-019-0008-y