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Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma

BACKGROUND: Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine carcinoma of the skin caused by either the integration of Merkel cell polyomavirus (MCPyV) and expression of viral T antigens or by ultraviolet-induced damage to the tumor genome from excessive sunlight exposure. An increa...

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Detalles Bibliográficos
Autores principales: Starrett, Gabriel J., Thakuria, Manisha, Chen, Tianqi, Marcelus, Christina, Cheng, Jingwei, Nomburg, Jason, Thorner, Aaron R., Slevin, Michael K., Powers, Winslow, Burns, Robert T., Perry, Caitlin, Piris, Adriano, Kuo, Frank C., Rabinowits, Guilherme, Giobbie-Hurder, Anita, MacConaill, Laura E., DeCaprio, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081548/
https://www.ncbi.nlm.nih.gov/pubmed/32188490
http://dx.doi.org/10.1186/s13073-020-00727-4