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Tubular bile duct structure mimicking bile duct morphogenesis for prospective in vitro liver metabolite recovery

BACKGROUND: Liver metabolites are used to diagnose disease and examine drugs in clinical pharmacokinetics. Therefore, development of an in vitro assay system that reproduces liver metabolite recovery would provide important benefits to pharmaceutical research. However, liver models have proven chall...

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Detalles Bibliográficos
Autores principales: Rizki-Safitri, Astia, Shinohara, Marie, Tanaka, Minoru, Sakai, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081557/
https://www.ncbi.nlm.nih.gov/pubmed/32206088
http://dx.doi.org/10.1186/s13036-020-0230-z