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Synthesis of Stable Cholesteryl–Polyethylene Glycol–Peptide Conjugates with Non-Disperse Polyethylene Glycol Lengths

[Image: see text] A method for conjugating cholesterol to peptide ligands through non-disperse polyethylene glycol (ND-PEG) through a non-hydrolysable linkage is described. The iterative addition of tetraethylene glycol macrocyclic sulfate to cholesterol (Chol) renders a family of highly pure well-d...

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Detalles Bibliográficos
Autores principales: Cristóbal-Lecina, Edgar, Pulido, Daniel, Martin-Malpartida, Pau, Macias, Maria J., Albericio, Fernando, Royo, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081636/
https://www.ncbi.nlm.nih.gov/pubmed/32201843
http://dx.doi.org/10.1021/acsomega.0c00130