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Overexpression of Karyopherin Subunit alpha 2 (KPNA2) Predicts Unfavorable Prognosis and Promotes Bladder Cancer Tumorigenicity via the P53 Pathway

BACKGROUND: We sought to investigate the expression of KPNA2 in bladder cancer (BC) and its relationship with prognosis, and to analyze the potential mechanism of KPNA2 in promoting BC progression. MATERIAL/METHODS: The RNA-seq data on BC from The Cancer Genome Atlas (TCGA) database were imported in...

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Detalles Bibliográficos
Autores principales: Shi, Changlong, Sun, Li, Liu, Shaozhuang, Zhang, Enchong, Song, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081662/
https://www.ncbi.nlm.nih.gov/pubmed/32147666
http://dx.doi.org/10.12659/MSM.921087