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Metastatic breast cancer cells induce altered microglial morphology and electrical excitability in vivo

BACKGROUND: An emerging problem in the treatment of breast cancer is the increasing incidence of metastases to the brain. Metastatic brain tumours are incurable and can cause epileptic seizures and cognitive impairment, so better understanding of this niche, and the cellular mechanisms, is urgently...

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Detalles Bibliográficos
Autores principales: Simon, Anna, Yang, Ming, Marrison, Joanne L., James, Andrew D., Hunt, Mark J., O’Toole, Peter J., Kaye, Paul M., Whittington, Miles A., Chawla, Sangeeta, Brackenbury, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081703/
https://www.ncbi.nlm.nih.gov/pubmed/32192526
http://dx.doi.org/10.1186/s12974-020-01753-0