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Metastatic breast cancer cells induce altered microglial morphology and electrical excitability in vivo
BACKGROUND: An emerging problem in the treatment of breast cancer is the increasing incidence of metastases to the brain. Metastatic brain tumours are incurable and can cause epileptic seizures and cognitive impairment, so better understanding of this niche, and the cellular mechanisms, is urgently...
Autores principales: | Simon, Anna, Yang, Ming, Marrison, Joanne L., James, Andrew D., Hunt, Mark J., O’Toole, Peter J., Kaye, Paul M., Whittington, Miles A., Chawla, Sangeeta, Brackenbury, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081703/ https://www.ncbi.nlm.nih.gov/pubmed/32192526 http://dx.doi.org/10.1186/s12974-020-01753-0 |
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