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The interrupted effect of autophagic flux and lysosomal function induced by graphene oxide in p62-dependent apoptosis of F98 cells

BACKGROUND: Graphene oxide (GO) nanoparticles (NPs) have been widely applied in various fields, especially in biomedical applications. Extensive studies have suggested that GO can pass through the blood–brain barrier (BBB) and induce abnormal autophagy and cytotoxicity in the central nervous system...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Feng, Xiaoli, He, Longwen, Zhang, Yaqing, Shao, Longquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081710/
https://www.ncbi.nlm.nih.gov/pubmed/32188458
http://dx.doi.org/10.1186/s12951-020-00605-6