The Specific Impact of Apolipoprotein E Epsilon 2 on Cognition and Brain Function in Cognitively Normal Elders and Mild Cognitive Impairment Patients

Variants in the apolipoprotein E (APOE) gene play an important role in the development of Alzheimer’s disease (AD). Specifically, the APOE ε4 allele is an established genetic risk factor for AD, while the APOE ε2 allele is a protective factor against AD. However, the mechanism underlying this impact...

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Detalles Bibliográficos
Autores principales: Gong, Liang, Xu, Ronghua, Liu, Duan, Lan, Lin, Zhang, Bei, Zhang, Chuantao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081769/
https://www.ncbi.nlm.nih.gov/pubmed/32226373
http://dx.doi.org/10.3389/fnagi.2019.00374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081769/
https://www.ncbi.nlm.nih.gov/pubmed/32226373
http://dx.doi.org/10.3389/fnagi.2019.00374

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