Cargando…

The Specific Impact of Apolipoprotein E Epsilon 2 on Cognition and Brain Function in Cognitively Normal Elders and Mild Cognitive Impairment Patients

Variants in the apolipoprotein E (APOE) gene play an important role in the development of Alzheimer’s disease (AD). Specifically, the APOE ε4 allele is an established genetic risk factor for AD, while the APOE ε2 allele is a protective factor against AD. However, the mechanism underlying this impact...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gong, Liang, Xu, Ronghua, Liu, Duan, Lan, Lin, Zhang, Bei, Zhang, Chuantao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081769/ https://www.ncbi.nlm.nih.gov/pubmed/32226373 http://dx.doi.org/10.3389/fnagi.2019.00374

Ejemplares similares

Effects of Gender and Apolipoprotein E on Novelty MMN and P3a in Healthy Elderly and Amnestic Mild Cognitive Impairment
por: Gao, Lijuan, et al.
Publicado: (2018)

The role of apolipoprotein E (APOE) genotype in early mild cognitive impairment (E-MCI)
por: Risacher, Shannon L., et al.
Publicado: (2013)

Apolipoprotein E ε4 Specifically Modulates the Hippocampus Functional Connectivity Network in Patients With Amnestic Mild Cognitive Impairment
por: Zhu, Lin, et al.
Publicado: (2018)

Clinical Relevance of Specific Cognitive Complaints in Determining Mild Cognitive Impairment from Cognitively Normal States in a Study of Healthy Elderly Controls
por: Ávila-Villanueva, Marina, et al.
Publicado: (2016)

The Effect of Apolipoprotein E ε4 (APOE ε4) on Visuospatial Working Memory in Healthy Elderly and Amnestic Mild Cognitive Impairment Patients: An Event-Related Potentials Study
por: Gu, Li-Hua, et al.
Publicado: (2017)

Apolipoprotein Eε4: A Biomarker for Executive Dysfunction among Parkinson's Disease Patients with Mild Cognitive Impairment
por: Samat, Nor A., et al.
Publicado: (2017)

Association of apolipoprotein E epsilon 4 and cognitive impairment in adults living with human immunodeficiency virus: a meta-analysis
por: Mu, Tingting, et al.
Publicado: (2022)

Dual-Model Radiomic Biomarkers Predict Development of Mild Cognitive Impairment Progression to Alzheimer’s Disease
por: Zhou, Hucheng, et al.
Publicado: (2019)

Telmisartan and Rosuvastatin Synergistically Ameliorate Dementia and Cognitive Impairment in Older Hypertensive Patients With Apolipoprotein E Genotype
por: Hu, Wenjing, et al.
Publicado: (2020)

Altered Functional Connectivity of the Basal Nucleus of Meynert in Subjective Cognitive Impairment, Early Mild Cognitive Impairment, and Late Mild Cognitive Impairment
por: Xu, Wenwen, et al.
Publicado: (2021)

Association between Thyroid Hormones, Apolipoprotein E, and Cognitive Function among Cognitively-Normal Elderly Dwellers
por: Kim, Beomjun, et al.
Publicado: (2020)

Magnetization Transfer Ratio Relates to Cognitive Impairment in Normal Elderly
por: Seiler, Stephan, et al.
Publicado: (2014)

Coronary artery disease and plasma apolipoprotein E4 in mild cognitive impairment
por: Barekatain, Majid, et al.
Publicado: (2014)

Inhibitory Control of Saccadic Eye Movements and Cognitive Impairment in Mild Cognitive Impairment
por: Opwonya, Julius, et al.
Publicado: (2022)

A Large, Cross-Sectional Observational Study of Serum BDNF, Cognitive Function, and Mild Cognitive Impairment in the Elderly
por: Shimada, Hiroyuki, et al.
Publicado: (2014)

Altered Cingulate Cortex Functional Connectivity in Normal Aging and Mild Cognitive Impairment
por: Cera, Nicoletta, et al.
Publicado: (2019)

Correlation Between Gait and Near-Infrared Brain Functional Connectivity Under Cognitive Tasks in Elderly Subjects With Mild Cognitive Impairment
por: Liu, Ying, et al.
Publicado: (2021)

Neuropsychiatric Profile as a Predictor of Cognitive Decline in Mild Cognitive Impairment
por: Roberto, Natalia, et al.
Publicado: (2021)

Overlap Between Apolipoprotein Eε4 Allele and Slowing Gait Results in Cognitive Impairment
por: Sakurai, Ryota, et al.
Publicado: (2019)

Cognitive training based on functional near-infrared spectroscopy neurofeedback for the elderly with mild cognitive impairment: a preliminary study
por: Lee, Ilju, et al.
Publicado: (2023)

Effects of motor-cognitive interaction based on dual-task gait analysis recognition in middle age to aging people with normal cognition and mild cognitive impairment
por: Zheng, Yuxin, et al.
Publicado: (2022)

Apolipoprotein E4 effects on topological brain network organization in mild cognitive impairment
por: Sanabria-Diaz, Gretel, et al.
Publicado: (2021)

Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment
por: Begcevic Brkovic, Ilijana, et al.
Publicado: (2022)

Mismatch Negativity Latency as a Biomarker of Amnestic Mild Cognitive Impairment in Chinese Rural Elders
por: Ji, Li-Li, et al.
Publicado: (2015)

Association between sedentary behavior and risk of cognitive decline or mild cognitive impairment among the elderly: a systematic review and meta-analysis
por: Cai, Xiao-ye, et al.
Publicado: (2023)

Mitigating effects and mechanisms of Tai Chi on mild cognitive impairment in the elderly
por: Wang, Xin, et al.
Publicado: (2023)

Subjective Cognitive Complaints in Newly-Diagnosed Parkinson’s Disease With and Without Mild Cognitive Impairment
por: Pan, Chenxi, et al.
Publicado: (2021)

Apolipoprotein E Induced Cognitive Dysfunction: Mediation Analysis of Lipids and Glucose Biomarkers in an Elderly Cohort Study
por: Liu, Linxin, et al.
Publicado: (2021)

Lack of Temporal Impairment in Patients With Mild Cognitive Impairment
por: Mioni, Giovanna, et al.
Publicado: (2019)

Divergent Roles of Vascular Burden and Neurodegeneration in the Cognitive Decline of Geriatric Depression Patients and Mild Cognitive Impairment Patients
por: Ye, Qing, et al.
Publicado: (2017)

Comparison of brain microstructure alterations on diffusion kurtosis imaging among Alzheimer’s disease, mild cognitive impairment, and cognitively normal individuals
por: Chu, Xiaoqi, et al.
Publicado: (2022)

Long-term associations between objective sleep quality and quantity and verbal memory performance in normal cognition and mild cognitive impairment
por: Skourti, Eleni, et al.
Publicado: (2023)

Incidence of Mild Cognitive Impairment and Dementia in Parkinson’s Disease: The Parkinson’s Disease Cognitive Impairment Study
por: Nicoletti, Alessandra, et al.
Publicado: (2019)

Exercise-Induced Cognitive Plasticity, Implications for Mild Cognitive Impairment and Alzheimer’s Disease
por: Foster, Philip P., et al.
Publicado: (2011)

Global Efficiency of Structural Networks Mediates Cognitive Control in Mild Cognitive Impairment
por: Berlot, Rok, et al.
Publicado: (2016)

Cognitive Profiles and Atrophy Ratings on MRI in Senior Patients With Mild Cognitive Impairment
por: Flak, Marianne M., et al.
Publicado: (2018)

(18)F-Florbetaben Amyloid PET Imaging: A Chinese Study in Cognitive Normal Controls, Mild Cognitive Impairment, and Alzheimer’s Disease Patients
por: Chang, Yan, et al.
Publicado: (2020)

The Effects of a Magic Intervention Program on Cognitive Function and Neurocognitive Performance in Elderly Individuals With Mild Cognitive Impairment
por: Lee, Kuan-Ting, et al.
Publicado: (2022)

SMR/Theta Neurofeedback Training Improves Cognitive Performance and EEG Activity in Elderly With Mild Cognitive Impairment: A Pilot Study
por: Marlats, Fabienne, et al.
Publicado: (2020)

Graph analysis of verbal fluency test discriminate between patients with Alzheimer's disease, mild cognitive impairment and normal elderly controls
por: Bertola, Laiss, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9uhgrb52onok19f1s79a3nssfq