Evasion of a Human Cytomegalovirus Entry Inhibitor with Potent Cysteine Reactivity Is Concomitant with the Utilization of a Heparan Sulfate Proteoglycan-Independent Route of Entry

The dependence of viruses on the host cell to complete their replicative cycle renders cellular functions potential targets for novel antivirals. We screened a panel of broadly acting cellular ion channel inhibitors for activity against human cytomegalovirus (HCMV) and identified the voltage-gated c...

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Detalles Bibliográficos
Autores principales: Murray, M. J., Bonilla-Medrano, N. I., Lee, Q. L., Oxenford, S. J., Angell, R., Depledge, D. P., Reeves, M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081914/
https://www.ncbi.nlm.nih.gov/pubmed/31941787
http://dx.doi.org/10.1128/JVI.02012-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081914/
https://www.ncbi.nlm.nih.gov/pubmed/31941787
http://dx.doi.org/10.1128/JVI.02012-19

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