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Evasion of a Human Cytomegalovirus Entry Inhibitor with Potent Cysteine Reactivity Is Concomitant with the Utilization of a Heparan Sulfate Proteoglycan-Independent Route of Entry
The dependence of viruses on the host cell to complete their replicative cycle renders cellular functions potential targets for novel antivirals. We screened a panel of broadly acting cellular ion channel inhibitors for activity against human cytomegalovirus (HCMV) and identified the voltage-gated c...
Autores principales: | Murray, M. J., Bonilla-Medrano, N. I., Lee, Q. L., Oxenford, S. J., Angell, R., Depledge, D. P., Reeves, M. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081914/ https://www.ncbi.nlm.nih.gov/pubmed/31941787 http://dx.doi.org/10.1128/JVI.02012-19 |
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