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Engineering a novel endopeptidase based on SARS 3CL(pro)
A 3C-like protease (3CL(pro)) from the severe acute respiratory syndrome–coronavirus (SARS-CoV) is required for viral replication, cleaving the replicase polyproteins at 11 sites with the conserved Gln↓(Ser, Ala, Gly) sequences. In this study, we developed a mutant 3CL(pro) (T25G) with an expanded S...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Future Science Ltd
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7081961/ https://www.ncbi.nlm.nih.gov/pubmed/20041855 http://dx.doi.org/10.2144/000113303 |