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Crystal structure of Mokola virus glycoprotein in its post-fusion conformation

Mokola virus (MOKV) belongs to the lyssavirus genus. As other genus members—including rabies virus (RABV)—it causes deadly encephalitis in mammals. MOKV entry into host cells is mediated by its transmembrane glycoprotein G. First, G binds cellular receptors, triggering virion endocytosis. Then, in t...

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Detalles Bibliográficos
Autores principales: Belot, Laura, Ouldali, Malika, Roche, Stéphane, Legrand, Pierre, Gaudin, Yves, Albertini, Aurélie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082061/
https://www.ncbi.nlm.nih.gov/pubmed/32150590
http://dx.doi.org/10.1371/journal.ppat.1008383