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Chromosomal rearrangements and their neoantigenic potential in mesothelioma

Chromosomal rearrangements are a defining molecular feature of mesothelioma that are not readily detected by standard DNA sequencing approaches but could be detected by whole genome sequencing methods such as mate-pair sequencing. These chromosomal rearrangements result in novel, unique gene junctio...

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Detalles Bibliográficos
Autores principales: Mansfield, Aaron Scott, Peikert, Tobias, Vasmatzis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082253/
https://www.ncbi.nlm.nih.gov/pubmed/32206575
http://dx.doi.org/10.21037/tlcr.2019.11.12