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Targeted sequencing analysis of cell-free DNA from metastatic non-small-cell lung cancer patients: clinical and biological implications

BACKGROUND: Sequencing artifacts, clonal hematopoietic mutations of indeterminate potential (CHIP) and tumor heterogeneity have been hypothesized to contribute to the low concordance between tissue and cell-free DNA (cfDNA) molecular profiling with targeted sequencing. METHODS: We analyzed by target...

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Detalles Bibliográficos
Autores principales: Pasquale, Raffaella, Forgione, Laura, Roma, Cristin, Fenizia, Francesca, Bergantino, Francesca, Rachiglio, Anna M., De Luca, Antonella, Gallo, Marianna, Maiello, Monica R., Palumbo, Giuliano, Morabito, Alessandro, Azzaro, Rosa, Normanno, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082281/
https://www.ncbi.nlm.nih.gov/pubmed/32206554
http://dx.doi.org/10.21037/tlcr.2020.01.01