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Emerging Role of the Autophagy/Lysosomal Degradative Pathway in Neurodevelopmental Disorders With Epilepsy

Autophagy is a highly conserved degradative process that conveys dysfunctional proteins, lipids, and organelles to lysosomes for degradation. The post-mitotic nature, complex and highly polarized morphology, and high degree of specialization of neurons make an efficient autophagy essential for their...

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Detalles Bibliográficos
Autores principales: Fassio, Anna, Falace, Antonio, Esposito, Alessandro, Aprile, Davide, Guerrini, Renzo, Benfenati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082311/
https://www.ncbi.nlm.nih.gov/pubmed/32231521
http://dx.doi.org/10.3389/fncel.2020.00039