Class II phosphatidylinositol 3-kinase α and β isoforms are required for vascular smooth muscle Rho activation, contraction and blood pressure regulation in mice

Class II phosphatidylinositol 3-kinases (PI3K), PI3K-C2α and PI3K-C2β, are involved in cellular processes including endocytosis, cilia formation and autophagy. However, the role of PI3K-C2α and PI3K-C2β at the organismal level is not well understood. We found that double knockout (KO) mice with both...

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Detalles Bibliográficos
Autores principales: Islam, Shahidul, Yoshioka, Kazuaki, Aki, Sho, Ishimaru, Kazuhiro, Yamada, Hiroki, Takuwa, Noriko, Takuwa, Yoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082390/
https://www.ncbi.nlm.nih.gov/pubmed/32192434
http://dx.doi.org/10.1186/s12576-020-00745-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082390/
https://www.ncbi.nlm.nih.gov/pubmed/32192434
http://dx.doi.org/10.1186/s12576-020-00745-2

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