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Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells

MicroRNAs (miRs) are one of the most important post-transcriptional repressors of gene expression. However, miR-574-5p has recently been shown to positively regulate the expression of microsomal prostaglandin E-synthase-1 (mPGES-1), a key enzyme in the prostaglandin E(2) (PGE(2)) biosynthesis, by ac...

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Detalles Bibliográficos
Autores principales: Emmerich, Anne C., Wellstein, Julia, Ossipova, Elena, Baumann, Isabell, Lengqvist, Johan, Kultima, Kim, Jakobsson, Per-Johan, Steinhilber, Dieter, Saul, Meike J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082395/
https://www.ncbi.nlm.nih.gov/pubmed/32231562
http://dx.doi.org/10.3389/fphar.2020.00196