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miR-122 Exerts Inhibitory Effects on Osteoblast Proliferation/Differentiation in Osteoporosis by Activating the PCP4-Mediated JNK Pathway

Osteoporosis is characterized by the reduction of bone mineral density and deterioration of bone quality which leads to high risk of fractures. Some microRNAs (miRNAs) have been confirmed as potential modulators of osteoblast differentiation to maintain bone mass maintenance. We aimed to clarify whe...

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Detalles Bibliográficos
Autores principales: Meng, Yi-Chen, Lin, Tao, Jiang, Heng, Zhang, Zheng, Shu, Lun, Yin, Jia, Ma, Xiao, Wang, Ce, Gao, Rui, Zhou, Xu-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082497/
https://www.ncbi.nlm.nih.gov/pubmed/32199130
http://dx.doi.org/10.1016/j.omtn.2019.11.038