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Beta cell identity changes with mild hyperglycemia: Implications for function, growth, and vulnerability
OBJECTIVE: As diabetes develops, marked reductions of insulin secretion are associated with very modest elevations of glucose. We wondered if these glucose changes disrupt beta cell differentiation enough to account for the altered function. METHODS: Rats were subjected to 90% partial pancreatectomi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082551/ https://www.ncbi.nlm.nih.gov/pubmed/32244186 http://dx.doi.org/10.1016/j.molmet.2020.02.002 |