Hypothalamic POMC deficiency increases circulating adiponectin despite obesity

OBJECTIVE: The steep rise in the prevalence of obesity and its related metabolic syndrome have become a major worldwide health concerns. Melanocortin peptides from hypothalamic arcuate nucleus (Arc) POMC neurons induce satiety to limit food intake. Consequently, Arc Pomc-deficient mice (ArcPomc(−/−)...

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Detalles Bibliográficos
Autores principales: Yu, Hui, Chhabra, Kavaljit H., Thompson, Zoe, Jones, Graham L., Kiran, Sylee, Shangguan, Gary, Low, Malcolm J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082555/
https://www.ncbi.nlm.nih.gov/pubmed/32244188
http://dx.doi.org/10.1016/j.molmet.2020.01.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082555/
https://www.ncbi.nlm.nih.gov/pubmed/32244188
http://dx.doi.org/10.1016/j.molmet.2020.01.021

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