The JNK inhibitor AS602801 Synergizes with Enzalutamide to Kill Prostate Cancer Cells In Vitro and In Vivo and Inhibit Androgen Receptor Expression()

In our previous study, we observed that androgen deprivation therapy (ADT) may induce a compensatory increase in MAPK or JNK signaling. Here, we tested the effects of the MEK inhibitors PD0325901 and GSK1120212, ERK1/2 inhibitor GDC-0994, and the JNK inhibitor AS602801 alone and in combination with...

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Detalles Bibliográficos
Autores principales: Li, Zhenghong, Sun, Carrie, Tao, Sijia, Osunkoya, Adeboye O., Arnold, Rebecca S., Petros, John A., Zu, Xiongbing, Moreno, Carlos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082632/
https://www.ncbi.nlm.nih.gov/pubmed/32199273
http://dx.doi.org/10.1016/j.tranon.2020.100751

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082632/
https://www.ncbi.nlm.nih.gov/pubmed/32199273
http://dx.doi.org/10.1016/j.tranon.2020.100751

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