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New emerging targets in cancer immunotherapy: CD27 (TNFRSF7)

Cluster of differentiation 27 (CD27) is a member of the tumour necrosis factor receptor superfamily and plays a key role in T-cell activation by providing a costimulatory signal. Bound to its natural ligand CD70, CD27 signalling enhances T-cell proliferation and differentiation to effector and memor...

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Detalles Bibliográficos
Autores principales: Starzer, Angelika M., Berghoff, Anna S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082637/
https://www.ncbi.nlm.nih.gov/pubmed/32152062
http://dx.doi.org/10.1136/esmoopen-2019-000629